1-AMino-1H-pyrrole-2-carboxylic acid aMide

1-AMino-1H-pyrrole-2-carboxylic acid aMide - Names and Identifiers

Name	1H-Pyrrole-2-carboxamide,1-amino-(9CI)
Synonyms	1-aminopyrrole-2-carboxamide 1-AMINO-1H-PYRROLE-2-CARBOXAMIDE 1H-Pyrrole-2-carboxamide, 1-amino- 1H-Pyrrole-2-carboxamide,1-amino-(9CI) 1-AMino-1H-pyrrole-2-carboxylic acid aMide
CAS	159326-69-9
InChI	InChI=1/C5H7N3O/c6-5(9)4-2-1-3-8(4)7/h1-3H,7H2,(H2,6,9)

1-AMino-1H-pyrrole-2-carboxylic acid aMide - Physico-chemical Properties

Molecular Formula	C5H7N3O
Molar Mass	125.13
Density	1.45±0.1 g/cm3(Predicted)
Boling Point	425.9±37.0 °C(Predicted)
Flash Point	211.375°C
Vapor Presure	0mmHg at 25°C
pKa	16.23±0.50(Predicted)
Storage Condition	2-8°C(protect from light)
Refractive Index	1.659

1-AMino-1H-pyrrole-2-carboxylic acid aMide - Introduction

The 1-amino-(9CI), also known as pyrrolidone, is an organic compound. The following is a description of some properties, uses, preparation and safety information about the compound:

Nature:
-Appearance: Colorless crystalline solid
-Molecular formula: C5H6N2O
-Molecular weight: 110.113g/mol
-Melting point: 148-150 ° C
-Boiling point: 359.8 ° C
-Insoluble in water, slightly soluble in many organic solvents, such as alcohols and ethers.

Use:
-, 1-amino-(9CI) is often used as an important intermediate in organic synthesis.
-It can be used to synthesize various pyrrole derivatives, such as indolinone and pyrrole-derived drugs.
-Pyrrolidone can also be used as a catalyst or reducing agent.

Method:
-A common preparation method is to react pyrrole-2-carbaldehyde, a precursor compound of pyrrolidone, with ammonia to obtain pyrrolidone.
-This reaction can be carried out in the presence of ammonia in an organic solvent, such as dimethylformamide (DMF) or tetrahydrofuran (THF).

Safety Information:
-, 1-amino-(9CI) is less toxic, but it may have an irritating effect on the eyes and skin.
-When operating, take appropriate safety measures, such as wearing chemical protective gloves and goggles, and ensure that the operating area is well ventilated.
-When handling this compound, avoid inhaling its dust or solution vapor.
-If taken by mistake or if skin contact occurs, rinse immediately with plenty of water and seek medical help.

Last Update：2024-04-09 15:17:53